Options at plateau include maintaining the current dose to prevent regain (the STEP 4 trial showed rapid weight regain after discontinuation), adding structured exercise to increase energy expenditure, reviewing dietary quality rather than just quantity, and in some cases, considering a temporary dose increase if prescribed by a provider
Information available on dietary reference intakes for individuals using obesity medications is minimal 28 , and currently not well-evidenced
That said, sermorelin also supports improved body composition over time it just works more gradually
Some studies have suggested BPC-157 interacts with nitric oxide signaling pathways that regulate vascular function
Next are semaglutide-based medications , Wegovy and Ozempic, then liraglutide-based options, Saxenda and Victoza
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